The purpose of this study is to understand how mental health develops and to know risk factors of mental health issues which are important in the effort of predicting, preventing, and also the intervention of the mental health issue that arises among adolescents. Adolescents have their challenges in their phase of transition from childhood to adulthood. This study reviewed the factors that contributed to the development of mental health and risk factors of mental disorders or issues among adolescents. The articles were obtained from Scopus, EBSCOhost ERIC, PsycARTICLES, and ResearchGate by searching using specific keywords: Mental Health, Adolescent, Youth, Factors, and Disorders. A total of 1394 article journals were found from the database search and 10 article journals were eligible for a systematic review after screening processes that involve in including quantitative studies that focused on risk factors of mental disorders and factors of mental health development, with adolescents as the samples. Findings revealed four core themes which are among the factors that contribute to youth mental health development or mental health issues; (a) family institution, (b) negative experience in life, (c) school or environmental factors, and (d) socioeconomic status. With the information provided from this study, the researchers suggest that a specific study have to be conducted focusing on a more comprehensive view of mental health development of adolescence and specific study that would focus on either family-based, school-based, and other specific dimensions to provide intervention and address the risk factors of youth mental health issues.