This study investigates how social tolerance, digital competence, religiosity, and social media access influence political apathy among Muslim Generation Z (Gen Z) students in Southern Sumatra—a region experiencing rapid digital transformation and characterized by rich social and cultural diversity. These four variables are considered key determinants of political apathy in this context. The research gains further relevance in light of the 2024 elections, which see heightened involvement from the youth demographic. Data were collected from 528 students across eight purposively selected campuses and analyzed using quantitative methods in R. The results show that digital competence significantly reduces political apathy, indicating that students with stronger digital skills are more likely to participate in political processes. However, social tolerance, religiosity, and social media access did not show a statistically significant impact. These findings highlight the need to enhance digital literacy among young people to encourage greater political engagement. The study recommends integrating digital literacy and civic education into school and university curricula to foster political participation and support pluralism in Indonesia’s multicultural society.